Tel: +86-181 3837 3963 (Whatsapp, Wechat) | contact@jctmixing.com
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Tel: +86-181 3837 3963 (Whatsapp, Wechat) | contact@jctmixing.com
Vertical kneader offers irreplaceable technical advantages for the medical device and pharmaceutical consumables industries, which require strict control over zero metal-ion contamination and zero shaft-seal leakage, as well as high-vacuum degassing capabilities.
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In the R&D and production of medical polymer materials (such as teeth resins, bone cements, medical-grade silicone rubber, and bio-hydrogels), vertical kneader serve as core equipment for mixing ultra-high-viscosity sterile materials in compliance with GMP standards.
JCT's mixing equipment is used in the pharmaceutical industry, primarily for high-viscosity dental materials (such as dental impression materials and light-curing resins for cavities) and paste-based products (such as transdermal preparations and wound-sealing pastes); vertical kneader can be used to replace sigma mixer.
Medical Polymer Materials Vertical Kneader Equipment Parameters
| Model | Dimension H*L*W /mm Weight | Barrel Inner Size D*H /mm | Full Volume /L | Useful Volume /L | Min Volume /L | Power /KW | Pericentric Blade Speed /rpm | Telecentric Blade Speed /rpm | Revolution Speed /rpm | Clearance /MM | Vacuum Abs Pressure /kPa |
| VK-10 | 2600*1600*1400 2.5t | 300*240 | 16.9 | 12 | 2 | 5.5 | 0~25 | 0~50 | 0~6 | 3±0.5 | <1.5 |
| VK-100 | 3200*2000*1600 6t | 600*480 | 135 | 100 | 15 | 22 | 0~25 | 0~50 | 0~6 | 4.5±0.5 | <1.5 |
| VK-500 | 4200*2500*2000 12t | 900*800 | 500 | 350 | 60 | 37 | 0~22.5 | 0~45 | 0~6 | 5.5±0.5 | <1.5 |
| VK-1000 | 5100*3000*2500 24t | 1200*1100 | 1000 | 600 | 120 | 45 | 0~22.5 | 0~45 | 0~6 | 6±1 | <1.5 |
| VK-2000 | 6000*4200*3000 32t | 1400*1300 | 2000 | 1200 | 200 | 55 | 0~20 | 0~40 | 0~6 | 7±1 | <1.5 |
| VK-3000 | 6500*4600*3400 35t | 1600*1500 | 3000 | 1800 | 300 | 75 | 0~20 | 0~40 | 0~5 | 8±1 | <1.5 |
| VK-5000 | 7300*5000*3600 40t | 1900*1800 | 5000 | 3000 | 500 | 110 | 0~18 | 0~36 | 0~5 | 9±1 | <1.5 |
01 Solvent-free processing
Eliminates the need for solvents, facilitating easy material synthesis and mixing while reducing toxicity, energy consumption, and pollution.
02 Ultra-high vacuum
Effectively removes low-molecular-weight polymers generated during polymerization.
03 No material contamination
Only the mixing blades and the vessel come into contact with the material, preventing contamination by foreign matter.
04 High-quality finished products
Delivers superior purity, strength, toughness, and uniformity compared to other equipment.
05 Increased solids content
Allows for higher filler loading, reducing material costs and enhancing product performance.
06 High-efficiency production
Utilizes multiple vessels in rotation, facilitating easy discharging and cleaning.
1. Dental compounds
Highly filled dental composite resins and glass ionomer cements possess extremely high viscosity. The powerful shear forces generated by a vertical kneader enable the perfect dispersion of ultrafine silica or glass powders into the viscous resin matrix without damaging sensitive polymer segments.
2. Medical-grade liquid silicone rubber (LSR/medical silicone)
Commonly used in the manufacture of respiratory masks, medical catheters, implants, and pharmaceutical seals. Vertical kneader enables the uniform incorportation of reinforcing fillers —such as fumed silica—and APIs (Active Pharmaceutical Ingredients) into high-viscosity silicone A/B components under high-vacuum conditions.
3. Medical bone cement (PMMA bone cement)
The mixing of bone cement demands exceptional uniformity. Vertical kneading ensures that the polymethyl methacrylate (PMMA) powder and liquid monomer are completely wetted and degassed within a very short time, thereby preventing structural weaknesses at the interface caused by air bubbles.
4. Medical-grade hydrogels and hyaluronic acid
For high-viscoelasticity materials such as cross-linked hyaluronic acid, vertical kneader provides gentle yet efficient kneading, preventing excessive shear that could damage the cross-linked network.
Structural Characteristics of Medical Polymer Materials Vertical Kneader
| Contamination Risk at the Sealed Shaft End | Vacuum Retention | Discharge and Cleaning (CIP/SIP) | Temperature Control Precision |
| Zero risk: The drive mechanism and seals are positioned entirely above the material, ensuring the material never comes into contact with the shaft seal and completely eliminating the risk of cross-contamination | Minimal dynamic seals and reliance on static seals facilitate the maintenance of a sustained high vacuum (exceeding -0.098 MPa), ensuring optimal degassing | The vessel body can be lowered and moved as a single unit; the absence of discharge dead zones makes thorough cleaning and Sterilization-in-Place (SIP) extremely convenient | The combination of a vessel jacket and agitator blades—which scrape the vessel walls to circulate the material—ensures uniform heat transfer and allows for precise temperature control within ±1°C |
Contact us to customized your medical polymer materials vertical kneader!
Tel: +86-181 3837 3963 (Whatsapp, Wechat)
Email: contact@jctmixing.com
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